SPIRE

SPIRE holds data derived from ~100k metagenomic samples in 739 studies encompassing ~500Tbp of publicly available raw metagenomes. It holds five main data types: manually curated contextual data, including annotations against a custom microntology, and:

• ~16Tbp worth of metagenomic assemblies (contigs)
• ~35 billion metagenomic open reading frames (ORFs) called from these contigs, functionally annotated in various ways
• 1.16 million metagenome-assembled genomes (MAGs) of medium or high quality, co-clustered with isolate genomes into over 100 thousand species-level clusters
• a custom mOTUs reference database for taxonomic profiling against these species-level clusters

The aim of SPIRE is to provide an integrated view of microbial diversity at various taxonomic granularities, at genome and at gene level, across known microbial habitats.